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Combined Spinal Epidural Anesthesia (CSEA) was performed at L3-4 and L2-3 separately and was technically uneventful. more A 71-year-old woman was scheduled for total knee replacement on left side.Combined Spinal Epidural Anesthesia (CSEA) was performed at L3-4 and L2-3 separately and was technically uneventful.A 22 years old, 158 cm of height, 40 kg weight, female, was under Spinal Anesthesia for tibia reconstruction on the right leg. The patient had a right tibia fracture, scheduled for tibia fixation.
Epidural Anesthesia (EA) with levobupivacaine 0.1% fentanyl (2mcg/ml) was effective at 5 ml/h for postoperative analgesia.
Eight hours post-op, she complained of having lost all feeling on the non-operative leg.
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Most patients undergoing TURP are elderly and frequently present with cardiopulmonary and endocrine diseases.
Listing a study does not mean it has been evaluated by the U. Low-dose local anesthetic is commonly administer to limit the block level to minimize the hemodynamic changes.
In our previous study, low-dose diluted bupivacaine 5 mg provided sufficient anesthetic level when opioid was added with local anesthetic.
However, opioid-induced side effects, such as pruritus, nausea, or vomiting, could be an obstacle in common use.
Previous clinical studies showed that intravenous dexmedetomidine administration prolonged the sensory and motor blocks of bupivacaine spinal analgesia.
But clinical studies about the use of intrathecal DXM with local anesthesia in humans are scarce in the literature. found that 3μg DXM added to 12 mg spinal bupivacaine produced the significant short onset of sensory and motor block as well as significantly longer duration of sensory and motor block than bupivacaine. reported that intrathecal dexmedetomidine as an adjuvant to 12.5mg bupivacaine in spinal anesthesia has a dose dependant effect on the onset and regression of sensory and motor block.
Patients were randomly allocated to DXM group or Saline group.
DMT group received hyperbaric bupivacaine 0.5% (1.2 ml) (6 mg) in dextrose 8% solution DMT 0.3 ml (3 µg)－in total, bupivacaine 0.4% (1.5 ml) intrathecally and Saline group received hyperbaric bupivacaine 0.5% (1.2 ml) (6 mg) in dextrose 8% solution normal saline 0.3 ml －in total, bupivacaine 0.4% (1.5 ml) intrathecally.